HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dichlorophenyl isocyanate → HCID 12608476, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dichlorophenyl isocyanate | HCID 7607 | — |
| Reactant | 3-[2-(4-Aminopiperidyl)ethyl]indole, hydrate | HCID 20384353 | — |
| Product | HCID 12608476 | HCID 12608476 | 78.6% |
Reaction Steps
Condensation of 3-[2-(4-aminopiperidyl)ethyl]indole, hydrate (1.31 g.) and 3,4-dichlorophenyl isocyanate (0.99 g., 5% excess) in the manner of Example 1 gave the crude title compound (2.03 g.) from which a pure hydrochloride (1.70 g., m.p. 258.4°, dec.) was obtained by treatment with ethanolic HCl/ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04177279 |
| Source dataset | uspto-grants-1979_12 |
| ORD ID | ord-90e23f6e0b6e4aa6ad742de1f6534ce1 |
| Source note | uspto-grants-1979_12 |