2-Chloroquinoline-6-carbonitrile → N-[1-(6-cyanoquinolin-2-yl)pyrrolidin-3-yl]-2,2-dimethylpropanamide
Reaction equation
[CH3:14][C:15]([C:16](=[O:17])[NH:18][CH:19]1[CH2:20][NH:21][CH2:22][CH2:23]1)([CH3:24])[CH3:25].[Cl:1][c:2]1[n:3][c:4]2[cH:5][cH:6][c:7]([C:12]#[N:13])[cH:8][c:9]2[cH:10][cH:11]1>>[c:2]1([N:21]2[CH2:20][CH:19]([NH:18][C:16]([C:15]([CH3:14])([CH3:24])[CH3:25])=[O:17])[CH2:23][CH2:22]2)[n:3][c:4]2[cH:5][cH:6][c:7]([C:12]#[N:13])[cH:8][c:9]2[cH:10][cH:11]1Participants
3
Sources & evidence
- ORD record
- ord-4d6fe412d12e4ceb945d6ab0db3d5731
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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