4-Chlorophenyl isothiocyanate → HCID 20384354, compound

HRID 1447590Notes

Reaction equation

HRID 1447590 reaction equation
O.[NH2:2][CH:3]1[CH2:8][CH2:7][N:6]([CH2:9][CH2:10][C:11]2[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[NH:13][CH:12]=2)[CH2:5][CH2:4]1.[Cl:20][C:21]1[CH:26]=[CH:25][C:24]([N:27]=[C:28]=[S:29])=[CH:23][CH:22]=1>>[Cl:20][C:21]1[CH:26]=[CH:25][C:24]([NH:27][C:28]([NH:2][CH:3]2[CH2:8][CH2:7][N:6]([CH2:9][CH2:10][C:11]3[C:19]4[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=4)[NH:13][CH:12]=3)[CH2:5][CH2:4]2)=[S:29])=[CH:23][CH:22]=1

Participants

3

Reactant 2

HCID 164804-Chlorophenyl isothiocyanateHCID 203843533-[2-(4-Aminopiperidyl)ethyl]indole, hydrate

Product 1

HCID 20384354HCID 20384354, compound

Procedure

4-Amino-1-[2-(3-indolyl)ethyl]piperidine hydrate is treated with 4-chlorophenyl isothiocyanate in the manner described in Example 10 to obtain the title compound as the hydrochloride.

Sources & evidence

ORD record
ord-bd9f0d88b1e246d082dee04555ff02d3
Source dataset
uspto-grants-1979_12
Patent number
US04177279

Reaction notes

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