Allylamine → HCID 20383068, compound

Participants

Reaction Steps

A solution of 512 mg of the ethyl ester of 6-chloro-3,4-dihydro-4-hydroxy-2H-1-benzopyran-2-carboxylic acid, (prepared by treating the ethyl ester of 6-chloro-3,4-dihydro-4-oxo-2H-1-benzopyran-2-carboxylic acid (Witiak et al., supra) with sodium borohydride), 570 mg of 2-propenamine and 20 ml of ethanol was stirred at room temperature for 72 hours, then stirred for 3 hours while heated by a steam bath. The solvent was stripped off and the residue was crystallized from methylene chloride/hexane to give 7, as white crystals, mp: 129°-130.5° C.

Provenance & Evidence