Hydrazine, propyl- → HCID 54527749, 화합물

HRID 1447803노트

반응식

HRID 1447803 반응식
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]=[C:9]2[C:14](=O)[C:13](=[CH:16][C:17]3[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=3)[CH2:12][S:11][CH2:10]2)=[CH:4][CH:3]=1.[CH2:24]([NH:27][NH2:28])[CH2:25][CH3:26]>CO>[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[NH:28][N:27]([CH2:24][CH2:25][CH3:26])[C:14]3[C:13](=[CH:16][C:17]4[CH:22]=[CH:21][C:20]([CH3:23])=[CH:19][CH:18]=4)[CH2:12][S:11][CH2:10][C:9]2=3)=[CH:4][CH:3]=1

참가 물질

4

반응물 2

HCID 42007Hydrazine, propyl-HCID 545668043,5-Bis[(4-methylphenyl)methylidene]thian-4-one

생성물 1

HCID 54527749HCID 54527749, 화합물수율 73%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

A mixture of tetrahydro-3,5-bis-(4-methylphenylmethylene)-4H-thiopyran-4-one (6.7 g, 20 mmole) and n-propylhydrazine (1.6 g, 22 mmole) in methanol (250 ml) is heated at reflux temperature for 5 hours, then cooled overnight. The pale yellow precipitate is collected by filtration. The filtrate is concentrated to about 50 ml and additional precipitate is again collected by filtration and combined with the previous batch to give 5.5 g of a crude product mixture.

후처리

  1. temperatureis heated
  2. temperatureat reflux temperature for 5 hours
  3. temperaturecooled overnight
  4. filtrationThe pale yellow precipitate is collected by filtration
  5. concentrationThe filtrate is concentrated to about 50 ml and additional precipitate
  6. filtrationis again collected by filtration

출처 및 근거

ORD 기록
ord-014daa33d227416dab316ccf793bb426
출처 데이터셋
uspto-grants-1979_12
특허 번호
US04178379

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