Acetic Anhydride → HCID 54211861, compound

HRID 1447832Notes

Reaction equation

HRID 1447832 reaction equation
[OH:1][C:2]1[CH:3]=[CH:4][C:5]([NH2:11])=[C:6]2[C:10]=1[CH2:9][CH2:8][CH2:7]2.[C:12](OC(=O)C)(=[O:14])[CH3:13]>O>[C:12]([NH:11][C:5]1[CH:4]=[CH:3][C:2]([OH:1])=[C:10]2[C:6]=1[CH2:7][CH2:8][CH2:9]2)(=[O:14])[CH3:13]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 23451480HCID 23451480, compound

Product 1

HCID 54211861HCID 54211861, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 25 g of 7-hydroxy-4-amino indane and of 8 ml of acetic anhydride in 400 ml of iced water was stirred for 30 minutes. After filtering, the precipitate was washed with water and ethyl ether and was recrystallized in isopropanol.

Workup

  1. filtrationAfter filtering
  2. washthe precipitate was washed with water and ethyl ether
  3. customwas recrystallized in isopropanol

Sources & evidence

ORD record
ord-f4b5e069a49a4eb0ba39fe6a1e9e6c47
Source dataset
uspto-grants-1979_12
Patent number
US04178442

Reaction notes

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