3-Dimethylamino-3'-trifluoromethylacrylophenone → HCID 23329844, compound

HRID 1447903Notes

Reaction equation

HRID 1447903 reaction equation
[NH2:1][C:2]1[C:6]([C:7]([O:9][CH3:10])=[O:8])=[C:5]([CH3:11])[NH:4][N:3]=1.CN(C)[CH:14]=[CH:15][C:16]([C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([C:24]([F:27])([F:26])[F:25])[CH:19]=1)=O>>[CH3:11][C:5]1[C:6]([C:7]([O:9][CH3:10])=[O:8])=[C:2]2[N:1]=[CH:14][CH:15]=[C:16]([C:18]3[CH:19]=[C:20]([C:24]([F:25])([F:26])[F:27])[CH:21]=[CH:22][CH:23]=3)[N:3]2[N:4]=1

Participants

3

Reactant 2

HCID 7300243-Dimethylamino-3'-trifluoromethylacrylophenoneHCID 13834975Methyl 3-amino-5-methyl-1H-pyrazole-4-carboxylate

Product 1

HCID 23329844HCID 23329844, compound

Procedure

As for Example 1, methyl 3-amino-5-methylpyrazole-4-carboxylate is reacted with 3-dimethylamino-3'-(trifluoromethyl)-acrylophenone to give the product as crystals, m.p. 177°-179° C.

Sources & evidence

ORD record
ord-fb7ea7b0e66846e3809f972fe8e2cb07
Source dataset
uspto-grants-1979_12
Patent number
US04178449

Reaction notes

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