HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 3-Bromo-7-(alpha,alpha,alpha-trifluoro-m-tolyl)pyrazolo[1,5-a]pyrimidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 7-[3-(Trifluoromethyl)phenyl]pyrazolo[1,5-a]pyrimidine | HCID 19756203 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 3-Bromo-7-(alpha,alpha,alpha-trifluoro-m-tolyl)pyrazolo[1,5-a]pyrimidine | HCID 11473317 | — |
Reaction Steps
To a 0.01 mole sample of 7-(α,α,α-trifluoro-m-tolyl)-pyrazolo [1,5-a]pyrimidine in 50 ml. of dichloromethane is added 0.01 mole of bromine. After standing, the mixture is worked up as for Example 15 to give the product as crystals, m.p. 138°-140° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04178449 |
| Source dataset | uspto-grants-1979_12 |
| ORD ID | ord-ebb1f3b1fecc4b408832b437944f8458 |
| Source note | uspto-grants-1979_12 |