Thionyl Chloride → HCID 20343343, compound

HRID 1447928Notes

Reaction equation

HRID 1447928 reaction equation
S(Cl)([Cl:3])=O.[F:5][C:6]([F:21])([F:20])[O:7][C:8]1[CH:19]=[CH:18][C:11]([CH:12](O)[C:13]([CH3:16])([CH3:15])[CH3:14])=[CH:10][CH:9]=1>>[Cl:3][CH:12]([C:11]1[CH:18]=[CH:19][C:8]([O:7][C:6]([F:21])([F:20])[F:5])=[CH:9][CH:10]=1)[C:13]([CH3:16])([CH3:15])[CH3:14]

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 54195762HCID 54195762, compound

Product 1

HCID 20343343HCID 20343343, compound

Procedure

To freshly distilled thionyl chloride (14.87 g, 0.125 mol) cooled in salt ice bath is added in portions the neopentyl alcohol of Example 24 (12.4 g, 0.05 mol) over 30 minutes. The ice bath is removed and the slurry is left to stand overnight. Evaporation of excess thionyl chloride gives a solid.

Workup

  1. customThe ice bath is removed
  2. waitthe slurry is left
  3. customEvaporation of excess thionyl chloride
  4. customgives a solid

Sources & evidence

ORD record
ord-f97e0fa9408648b6891fdb2e383aa868
Source dataset
uspto-grants-1979_12
Patent number
US04178460

Reaction notes

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