Carbon Dioxide → HCID 20343289, compound
Reaction equation
Cl[CH:2]([C:7]1[CH:12]=[CH:11][C:10]([O:13][C:14]([F:17])([F:16])[F:15])=[CH:9][CH:8]=1)[C:3]([CH3:6])([CH3:5])[CH3:4].[C:18](=[O:20])=[O:19]>>[C:3]([CH:2]([C:7]1[CH:12]=[CH:11][C:10]([O:13][C:14]([F:17])([F:16])[F:15])=[CH:9][CH:8]=1)[C:18]([OH:20])=[O:19])([CH3:6])([CH3:5])[CH3:4]Participants
3
Procedure
The neopentyl chloride prepared in Example 25 is converted to the Grignard reagent and subsequent carbonation with carbon dioxide according to the procedure of Weinstein and Morse [Journal of the American Chemical Society 74, 1133 (1952)] gives the desired acid as a white solid.
Sources & evidence
- ORD record
- ord-c21b6e22c8bd4ea3a24e022d3d976aec
- Source dataset
- uspto-grants-1979_12
- Patent number
- US04178460
Reaction notes
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