Water → 4,5-dichloro-imidazol-2-oyl-N,N'-diethylurea

HRID 1447963Notes

Reaction equation

HRID 1447963 reaction equation
[Cl:1][C:2]1[C:6]([Cl:7])=[N:5][C:4](=[C:8](Cl)Cl)[N:3]=1.[CH2:11]([NH:13][C:14]([NH:16][CH2:17][CH3:18])=[O:15])[CH3:12].[OH2:19]>>[Cl:1][C:2]1[N:3]=[C:4]([C:8]([N:13]([CH2:11][CH3:12])[C:14]([NH:16][CH2:17][CH3:18])=[O:15])=[O:19])[NH:5][C:6]=1[Cl:7]

Participants

4

Reactant 3

HCID 962WaterHCID 12194sym-DiethylureaHCID 124825724,5-Dichloro-2-(dichloromethylidene)-2H-imidazole

Product 1

HCID 205119244,5-dichloro-imidazol-2-oyl-N,N'-diethylureaYield 66%

Conditions

Temperature
100 °C

Procedure

21.8 g (0.1 mol) of 4,5-dichloro-2-dichloromethyleneimidazole were added to a solution of 26 g (0.22 mol) of N,N'-diethylurea in 150 ml of water and the mixture was heated to 100° C. while stirring. After cooling, the product was filtered off, washed with water and dried. In this way, 18.5 g (66% of theory) of 4,5-dichloro-imidazol-2-oyl-N,N'-diethylurea with a melting point of 159° C. were obtained.

Workup

  1. temperatureAfter cooling
  2. filtrationthe product was filtered off
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-69c9da7e204b44dda8a9d90a06f3a728
Source dataset
uspto-grants-1979_12
Patent number
US04179277

Reaction notes

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