Carbamic acid, ethyl ester → HCID 53993899, compound

HRID 1447964Notes

Reaction equation

HRID 1447964 reaction equation
[CH2:1]([O:3][C:4](=[O:6])[NH2:5])[CH3:2].[Cl:7][C:8]1[C:12]([Cl:13])=[N:11][C:10](=[C:14](Cl)Cl)[N:9]=1.[O:17]1CCOCC1>>[CH2:1]([O:3][C:4](=[O:6])[NH:5][C:14]([C:10]1[NH:11][C:12]([Cl:13])=[C:8]([Cl:7])[N:9]=1)=[O:17])[CH3:2]

Participants

4

Reactant 3

HCID 5641Carbamic acid, ethyl esterHCID 312751,4-DioxaneHCID 124825724,5-Dichloro-2-(dichloromethylidene)-2H-imidazole

Product 1

HCID 53993899HCID 53993899, compoundYield 60%

Procedure

A solution of 20 g (0.225 mol) of carbamic acid ethyl ester and 21.8 g (0.1 mol) of 4,5-dichloro-2-dichloromethylene-imidazole in 50 ml of dioxane was heated briefly to the boil (about 115° C.) After cooling, the product was precipitated with water, filtered off, washed with water and dried. 15 g (60% of theory) of N-(4,5-dichloroimidazol-2-oyl)-carbamic acid ethyl ester with a melting point of 208° C. (from acetonitrile) were obtained.

Workup

  1. temperatureAfter cooling
  2. customthe product was precipitated with water
  3. filtrationfiltered off
  4. washwashed with water
  5. customdried

Sources & evidence

ORD record
ord-060706b0d9554f57b67806d206df8f96
Source dataset
uspto-grants-1979_12
Patent number
US04179277

Reaction notes

Loading…