Sodium Hydroxide → HCID 20380707, compound

HRID 1447973Notes

Reaction equation

HRID 1447973 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([O:10][CH2:11][CH:12]2[O:14][CH2:13]2)=[CH:6][CH:5]=1)([O-])=O.[OH-:15].[Na+]>C(O)(=O)C>[NH2:1][C:4]1[CH:9]=[CH:8][C:7]([O:15][CH2:13][CH:12]([OH:14])[CH2:11][O:10][CH2:13][CH:12]([OH:14])[CH2:11][O:10][C:7]2[CH:6]=[CH:5][C:4]([NH2:1])=[CH:9][CH:8]=2)=[CH:6][CH:5]=1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 213272-((4-Nitrophenoxy)methyl)oxirane

Product 1

HCID 20380707HCID 20380707, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

PEG (10 g) is treated at 50° with aliquots (20 ml) of 10% aqueous glycidyl p-nitrophenyl ether and with portions (10 ml) of 10% aqueous sodium hydoxide. After 36 hours the solution is neutralized with 2 N acetic acid and evaporated. The PEG ether is extracted from the residue with benzene and precipitated by the addition of excess petroleum ether (bp 30-40).

Workup

  1. customevaporated
  2. extractionThe PEG ether is extracted from the residue with benzene
  3. customprecipitated by the addition of excess petroleum ether (bp 30-40)

Sources & evidence

ORD record
ord-d1f8eca1d0fb43549ce767ba41ca4f81
Source dataset
uspto-grants-1979_12
Patent number
US04179337

Reaction notes

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