Nalpha-(2-acetylthiomethyl-5-aminopentanoyl)-L-lysine trifluoroacetate → Nalpha-(5-amino-2-mercaptomethylpentanoyl)-L-lysine

HRID 1448003Notes

Reaction equation

HRID 1448003 reaction equation
FC(F)(F)C(O)=O.C([S:11][CH2:12][CH:13]([CH2:26][CH2:27][CH2:28][NH2:29])[C:14]([NH:16][C@H:17]([C:23]([OH:25])=[O:24])[CH2:18][CH2:19][CH2:20][CH2:21][NH2:22])=[O:15])(=O)C.C(SCC(CCCN)C(N[C@H](C(O)=O)CCCNC(=N)N)=O)(=O)C>>[NH2:29][CH2:28][CH2:27][CH2:26][CH:13]([CH2:12][SH:11])[C:14]([NH:16][C@H:17]([C:23]([OH:25])=[O:24])[CH2:18][CH2:19][CH2:20][CH2:21][NH2:22])=[O:15]

Participants

3

Reactant 2

HCID 22805334Nalpha-(2-acetylthiomethyl-5-aminopentanoyl)-L-lysine trifluoroacetateHCID 178477073HCID 178477073, compound

Product 1

HCID 22805342Nalpha-(5-amino-2-mercaptomethylpentanoyl)-L-lysine

Procedure

By substituting Nα -(2-acetylthiomethyl-5-aminopentanoyl)-L-lysine trifluoroacetate for the Nα -(2-acetylthiomethyl-5-aminopentanoyl)-L-arginine in the procedure of Example 31, Nα -(5-amino-2-mercaptomethylpentanoyl)-L-lysine is obtained.

Sources & evidence

ORD record
ord-35c09f8948934909bf2abaf2cb1c1338
Source dataset
uspto-grants-1979_12
Patent number
US04179434

Reaction notes

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