N-tert-butyloxycarbonyl-S-p-methoxybenzyl-D-cysteinyl-L-proline tert-butyl ester → HCID 54330773, compound

HRID 1448006Notes

Reaction equation

HRID 1448006 reaction equation
C(OC([NH:8][C@@H:9]([C:21]([NH:23][C@H:24]([C:35]([OH:37])=[O:36])[CH2:25][C:26]1[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[NH:28][CH:27]=1)=[O:22])[CH2:10][S:11]CC1C=CC(OC)=CC=1)=O)(C)(C)C.C(OC(=O)[C@@H]1CCCN1C(=O)[C@@H](CSCC1C=CC(OC)=CC=1)NC(OC(C)(C)C)=O)(C)(C)C>>[NH2:8][C@@H:9]([C:21]([NH:23][C@H:24]([C:35]([OH:37])=[O:36])[CH2:25][C:26]1[C:34]2[C:29](=[CH:30][CH:31]=[CH:32][CH:33]=2)[NH:28][CH:27]=1)=[O:22])[CH2:10][SH:11]

Participants

3

Reactant 2

HCID 22805345N-tert-butyloxycarbonyl-S-p-methoxybenzyl-D-cysteinyl-L-proline tert-butyl esterHCID 22809500HCID 22809500, compound

Product 1

HCID 54330773HCID 54330773, compound

Procedure

By substituting N-tert-butyloxycarbonyl-S-p-methoxybenzyl-D-cysteinyl-L-tryptophane for the N-tert-butyloxycarbonyl-S-p-methoxybenzyl-D-cysteinyl-L-proline tert-butyl ester in the procedure of Example 2, D-cysteinyl-L-tryptophane is obtained.

Sources & evidence

ORD record
ord-4b4dca21863d4b87ba77cdb29ef52225
Source dataset
uspto-grants-1979_12
Patent number
US04179434

Reaction notes

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