HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1448086Generated: October 31, 2026
Dimethyl Sulfoxide → 3-Nitro-4-(propylamino)benzoic acid
https://huagongshe.com/reaction/1448086
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethyl Sulfoxide | HCID 679 | — |
| Reactant | Propylamine | HCID 7852 | — |
| Reactant | 4-Fluoro-3-nitrobenzoic acid | HCID 67987 | — |
| Solvent | Water | HCID 962 | — |
| Product | 3-Nitro-4-(propylamino)benzoic acid | HCID 11715556 | — |
Reaction Steps
A mixture of 7.1 parts of 4-fluoro-3-nitrobenzoic acid, 9.1 parts of 1-propanamine and 25 parts of dimethyl sulfoxide is stirred for 3 hours at 60° C. The reaction mixture is poured onto 150 parts of water. The precipitated product is filtered off, washed with water and dried, yielding 8.8 parts of 3-nitro-4-(propylamino)benzoic acid; mp. 208° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04179505 |
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| Source dataset | uspto-grants-1979_12 |
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| ORD ID | ord-78b0a58ae3b64669a9d98eac4a9069d6 |
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| Source note | uspto-grants-1979_12 |
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