HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Thionyl Chloride → (2E)-3-(3-Fluorophenyl)-2-propenoyl chloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Thionyl Chloride | HCID 24386 | — |
| Edukt | (2E)-3-(3-Fluorophenyl)-2-propenoic acid | HCID 1551219 | — |
| Lösungsmittel | Benzene | HCID 241 | — |
| Produkt | (2E)-3-(3-Fluorophenyl)-2-propenoyl chloride | HCID 5706470 | 94,7% |
Reaktionsschritte
A mixture of trans 3-fluorocinnamic acid (32.3 g), thionyl chloride (48 g) and dry benzene (300 ml) was heated at reflux for 2 hours. Solvent and excess thionyl chloride was removed by distillation at reduced pressure leaving trans 3-fluorocinnamoyl chloride (34 g) as the oil.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04179524 |
| Quelldatensatz | uspto-grants-1979_12 |
| ORD ID | ord-3d7e39f874674a269d87ab9d5cadac39 |
| Quellennotiz | uspto-grants-1979_12 |