HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethyl acetylenedicarboxylate → Dimethyl 5-hydroxypyrazolo[1,5-c]quinazoline-1,2-dicarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethyl acetylenedicarboxylate | HCID 12980 | — |
| Reactant | (3Z)-3-diazo-1H-indol-2-one | HCID 136455454 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | Dimethyl 5-hydroxypyrazolo[1,5-c]quinazoline-1,2-dicarboxylate | HCID 135401800 | — |
Reaction Steps
A solution of 4.8 g (0.03 mole) of 3-diazooxindole in 150 ml of warm (45°) benzene is treated with 5.10 g (0.036 mole) of dimethylacetylene dicarboxylate. After stirring for 6 hours at 45°, an additional 0.426 g (0.003 mole) of ester is added and reaction continued overnight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04179561 |
| Source dataset | uspto-grants-1979_12 |
| ORD ID | ord-8cfb9ffcc81b455b85c98a729c876ea3 |
| Source note | uspto-grants-1979_12 |