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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1448440Generated: November 1, 2026

Benzenepropanoic acid → Isopropyl 3-phenylpropionate

https://huagongshe.com/reaction/1448440

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenepropanoic acidHCID 107—
ReactantAcetic AcidHCID 176—
ReactantIsopropanolHCID 3776—
ReactantDicyclohexylcarbodiimideHCID 10868—
SolventPyridineHCID 1049—
ProductIsopropyl 3-phenylpropionateHCID 34749694%

Reaction Steps

To a mixture of 3-phenylpropionic acid (15.0 g) and isopropanol (6.61 g) in pyridine (30 ml) perchloric acid (0.150 g) and DCC (24.8 g) are added. After stirring at room temperature for 24 h acetic acid (10 ml) is added, and the reaction mixture is worked-up as described in Example 1 to give a 94% yield of isopropyl 3-phenylpropionate (b. p., see Example 2).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04180504
Source datasetuspto-grants-1979_12
ORD IDord-921dd62e7b874d999f7b6cdfec821df2
Source noteuspto-grants-1979_12