Acetic Anhydride → Urea, N-(2-chloroethyl)-N-nitroso-N'-(2,3,4-tri-O-acetyl-beta-D-xylopyranosyl)-

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Reaction Steps

1-(2-chloroethyl)-1-nitroso-3-(β-D-xylopyranosyl) urea (99mg) was acetylated with acetic anhydride and pyridine in the same manner as that used in Example 1(b). Crystallization from a mixture of chloroform and n-propanol yielded the titled compound (42 mg). Yield 29.4%. mp. 124.5°-125° C. (with decomposition). [α]D17 -19.0° (c 0.9, chloroform).

Provenance & Evidence