Acetone → HCID 12465924, compound

Participants

Reaction Steps

A mixture of 35 parts of 1,1,3-trichloro-1H-indene, 295 parts of 2-propanone, and 375 parts of water is heated at the boiling point under reflux in a nitrogen atmosphere overnight. The resultant dark brown solution is stripped of solvent by vacuum distillation under nitrogen at 35°. The distilland is extracted with 1,1'-oxybisethane. The extract is consecutively washed with water, 10% sodium chloride, and water, then dried over anhydrous magnesium sulfate and thereupon stripped of solvent by vacuum distillation. The oily residue is crystallized from pentane to give 3-chloro-1H-inden-1-one as a red-orange solid, the formula of which is ##STR4##

Provenance & Evidence