Triethyl orthoacetate → HCID 12669654, compound

Participants

Reaction Steps

A mixture of 1 part of 2-cyano-2-(3-hydroxy-1H-inden-1-ylidene)acetamide, 1 part of 1,1,1-triethoxyethane, and approximately 6 parts of N,N-dimethylformamide is heated at 90°-95° under reflux for 2 hours, whereupon the precipitate which forms is filtered out, washed with ethyl acetate, and dried in vacuo. Crystallization from ethyl acetate affords needles of 3,9-dihydro-1-methyl-3,9-dioxo-2H-indeno[2,1-c]pyridine-4-carbonitrile melting above 300°. The product has the formula ##STR7##

Provenance & Evidence