Sulfuric Acid → HCID 12669655, compound

HRID 1448568Notes

Reaction equation

HRID 1448568 reaction equation
[O:1]=[C:2]1[NH:7][CH:6]=[C:5]2[C:8](=[O:15])[C:9]3[CH:10]=[CH:11][CH:12]=[CH:13][C:14]=3[C:4]2=[C:3]1[C:16]#[N:17].S(=O)(=O)(O)[OH:19]>O>[O:1]=[C:2]1[NH:7][CH:6]=[C:5]2[C:8](=[O:15])[C:9]3[CH:10]=[CH:11][CH:12]=[CH:13][C:14]=3[C:4]2=[C:3]1[C:16]([NH2:17])=[O:19]

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 12669652HCID 12669652, compound

Product 1

HCID 12669655HCID 12669655, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

A mixture of 5 parts of 3,9-dihydro-3,9-dioxo-2H-indeno-[2,1-c]pyridine-4-carbonitrile, 46 parts of concentrated sulfuric acid, and 1 part of water is heated at 60°-65° for 41/2 hours, then slowly diluted with 200 parts of water. The copious precipitate which forms is filtered off, washed with water, and crystallized from acetic acid to give 3,9-dihydro-3,9-dioxo-2H-indeno[2,1-c]pyridine-4-carboxamide melting above 300°. The product has the formula ##STR16##

Workup

  1. temperatureis heated at 60°-65° for 41/2 hours
  2. filtrationThe copious precipitate which forms is filtered off
  3. washwashed with water
  4. customcrystallized from acetic acid

Sources & evidence

ORD record
ord-ee18cdabd76046199d0b2efc6592a84f
Source dataset
uspto-grants-1979_12
Patent number
US04180666

Reaction notes

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