Sulfuric Acid → HCID 12669657, compound

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Reaction Steps

A mixture of approximately 2 parts of 3,9-dihydro-1-methyl-3,9-dioxo-2H-indeno[2,1-c]pyridine-4-carbonitrile, 37 parts of concentrated sulfuric acid, and 1 part of water is heated at 90°-95° for 2 hours, then slowly diluted with 175 parts of water. The precipitate which forms is filtered off, washed with methanol, dried in vacuo, and crystallized from aqueous N,N-dimethylformamide to give 3,9-dihydro-1-methyl-3,9-dioxo-2H-indeno[2,1-c]pyridine-4-carboxamide as a pale yellow solid melting above 300°. The product has the formula ##STR17##

Provenance & Evidence