Water → HCID 20380612, compound

Participants

Reaction Steps

Phosphorus tribromide (18.0 g; 0.067 mol) is added dropwise at 10° C. to a stirred slurry of 4-chloro-2-methyl-3,5-dinitrobenzyl alcohol (50.0 g; 0.20 mol) in benzene (100 ml). The reaction mixture is allowed to warm to room temperature and then heated to reflux for 5 hours. After standing at room temperature overnight, the mixture is poured into water and extracted with ether. Insoluble material present is collected and dried to yield 18.9 g solid, melting point 115°-120° C. Removal of the ether from the extracts yields additional 38.6 g solid, melting point 106° C.-112° C.

Provenance & Evidence