Glycine → Boc-Phe-Gly-OH

HRID 1448701Notes

Reaction equation

HRID 1448701 reaction equation
[C:1]([O:5][C:6]([NH:8][C@H:9]([C:17]([OH:19])=O)[CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[NH2:20][CH2:21][C:22]([OH:24])=[O:23]>>[C:1]([O:5][C:6]([NH:8][C@H:9]([C:17]([NH:20][CH2:21][C:22]([OH:24])=[O:23])=[O:19])[CH2:10][C:11]1[CH:12]=[CH:13][CH:14]=[CH:15][CH:16]=1)=[O:7])([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 2

HCID 750GlycineHCID 77857L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]-

Product 1

HCID 7014899Boc-Phe-Gly-OH

Procedure

p-nitrophenyl ester of tert-butoxycarbonylphenylalanine is reacted with glycine to obtain tert-butoxycarbonylphenylalanylglycine;

Sources & evidence

ORD record
ord-1adac10246ad46578bc21875f66f5709
Source dataset
uspto-grants-1980_02
Patent number
US04187217

Reaction notes

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