Ethyl 3,7-dimethyl-8-oxoocta-2,4,6-trienoate → 9-(6-Chloro-4-methoxy2,5-dimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid ethyl ester

HRID 1448766Notes

Reaction equation

HRID 1448766 reaction equation
[Cl-].[Cl:2][C:3]1[C:8]([CH2:9][P+](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=[C:7]([CH3:29])[CH:6]=[C:5]([O:30][CH3:31])[C:4]=1[CH3:32].[CH2:33]([O:35][C:36](=[O:47])[CH:37]=[C:38]([CH3:46])[CH:39]=[CH:40][CH:41]=[C:42]([CH:44]=O)[CH3:43])[CH3:34]>>[CH2:33]([O:35][C:36](=[O:47])[CH:37]=[C:38]([CH3:46])[CH:39]=[CH:40][CH:41]=[C:42]([CH3:44])[CH:43]=[CH:9][C:8]1[C:3]([Cl:2])=[C:4]([CH3:32])[C:5]([O:30][CH3:31])=[CH:6][C:7]=1[CH3:29])[CH3:34]

Participants

3

Reactant 2

HCID 54295620Ethyl 3,7-dimethyl-8-oxoocta-2,4,6-trienoateHCID 86735156HCID 86735156, compound

Product 1

HCID 1353899-(6-Chloro-4-methoxy2,5-dimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid ethyl ester

Procedure

By the procedure of Example 1, 6-chloro-4-methoxy-2,5-dimethyl-benzyl-triphenylphosphonium chloride is reacted with 7-formyl-3-methyl-octa-2,4,6-trien-1-oic acid ethyl ester to obtain 9-(6-chloro-4-methoxy-2,5-dimethyl-phenyl)-3,7-dimethyl-nona-2,4,6,8-tetraen-1-oic acid ethyl ester of melting point 106°-107° C.

Sources & evidence

ORD record
ord-4eb9be987d38442ca830a5c9bccdda1f
Source dataset
uspto-grants-1980_02
Patent number
US04187247

Reaction notes

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