HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → tert-Butyl cyclohexa-2,5-diene-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 2,5-Cyclohexadiene-1-carboxylic acid | HCID 78522 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Catalyst | Dichloromethane | HCID 6344 | — |
| Solvent | Isobutylene | HCID 8255 | — |
| Product | tert-Butyl cyclohexa-2,5-diene-1-carboxylate | HCID 12375195 | — |
Reaction Steps
A solution of 16 g of 2,5-cyclohexadiene carboxylic acid in 20 ml of dichloromethane containing 10 drops of sulfuric acid is treated with 40 ml of isobutylene in an autoclave overnight after which the contents were poured into a sodium bicarbonate solution. The organic phase is isolated and passed through alumina to afford tert-butyl 2,5-cyclohexadienecarboxylate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04187316 |
| Source dataset | uspto-grants-1980_02 |
| ORD ID | ord-c7c5e82b84a04e319e31c26b8799c59c |
| Source note | uspto-grants-1980_02 |