Methyl iodide → HCID 2826927, compound

HRID 1448949Notes

Reaction equation

HRID 1448949 reaction equation
[CH3:1][C:2]1[C:3]2[N:4]([CH:8]=[CH:9][CH:10]=2)[CH2:5][CH2:6][N:7]=1.[CH3:11][I:12]>C(O)C>[I-:12].[CH3:1][C:2]1[C:3]2[N:4]([CH:8]=[CH:9][CH:10]=2)[CH2:5][CH2:6][N+:7]=1[CH3:11]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 5842861-Methyl-3,4-dihydropyrrolo[1,2-a]pyrazine

Product 1

HCID 2826927HCID 2826927, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A solution of 3,4-dihydro-1-methylpyrrolo(1,2-a)pyrazine (4.5 g, described in Example 2) and methyl iodide (9 ml) in ethanol (60 ml) is refluxed for 15 hr and evaporated. The residue is crystallized from methanol-diethyl ether to obtain 3,4-dihydro-1,2-dimethylpyrrolo(1,2-a)pyrazinium iodide (6.0 g), mp 166°-168° C.

Workup

  1. customevaporated
  2. customThe residue is crystallized from methanol-diethyl ether

Sources & evidence

ORD record
ord-583bd2b245ca466bb5baeaa0d4b79c89
Source dataset
uspto-grants-1980_02
Patent number
US04188389

Reaction notes

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