HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propionyl chloride → N-acetyl-4-(4-n-propylphenyl)-piperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propionyl chloride | HCID 62324 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Reactant | HCID 11608128 | HCID 11608128 | — |
| Reactant | N-acetyl-4-(4-propionylphenyl)-piperidine | HCID 13151836 | — |
| Product | N-acetyl-4-(4-n-propylphenyl)-piperidine | HCID 13151837 | — |
Reaction Steps
The starting material can be produced, for example, by reaction of 18 g of N-acetyl-4-phenyl-piperidine and 11.5 g of propionic acid chloride, in the presence of aluminium trichloride, to N-acetyl-4-(4-propionylphenyl)-piperidine and then catalytic hydrogenation thereof to give N-acetyl-4-(4-n-propylphenyl)-piperidine, b.p.0.03 =160°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04188396 |
| Source dataset | uspto-grants-1980_02 |
| ORD ID | ord-5d1e1cc345d741418c17f87d6815b6f2 |
| Source note | uspto-grants-1980_02 |