Diethyl Ether → HCID 20374791, compound

Participants

Reaction Steps

A mixture of 4,5-bis(4-fluorophenyl)-1H-imidazole-2-thione (8 g, 0.028 mol) and 1,3-dibromopropane (2.8 g, 0.014 mol) in dioxane (175 ml) was refluxed for 2.5 hours. After cooling, ether (300 ml) was added and the resulting white solid was collected by filtration, washed with ether and recrystallized from dioxane-ether to give the title compound as its dihydrobromide salt (hydrate), m.p. 176°-178°.

Provenance & Evidence