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HRID1449013

反应详情

EQUATION

反应方程式

HRID 1449013 的结构方程式

REACTANTS

反应物

3
结构：O=Cc1cccc(Cl)c1
HCID11477

Benzaldehyde, 3-chloro-

C7H5ClO

结构：CCOC(=O)/C=C(/C)N
HCID643756

未命名化合物

结构：CCOC(=O)CC(=O)CN1C(=O)c2ccccc2C1=O
HCID701239

Ethyl 4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-3-oxobutanoate

C14H13NO5

PRODUCTS

生成物

1
结构：CCOC(=O)C1=C(C)NC(CN2C(=O)c3ccccc3C2=O)=C(C(=O)OCC)C1c1cccc(Cl)c1
HCID70588791

未命名化合物

收率 55%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

28 g of 3-chlorobenzaldehyde, 56 g of phthalimidoacetoacetic acid ethyl ester and 25.8 g of β-aminocrotonic acid ethyl ester in 250 ccs of ethanol are heated to the boil under reflux for 3×24 hours, the mixture is allowed to cool, whilst stirring, and, after filtering, light yellow crystals of melting point 135°-136° C. are obtained, yield: 55%.

WORKUP

后处理

  1. temperatureunder reflux for 3×24 hours
  2. temperatureto cool
  3. filtrationafter filtering
  4. customlight yellow crystals of melting point 135°-136° C. are obtained