Fusaric Acid → HCID 20375060, compound

HRID 1449025Notes

Reaction equation

HRID 1449025 reaction equation
[C:1]1([NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[NH2:7].[CH3:9][CH2:10][CH2:11][CH2:12][C:13]1[CH:14]=[CH:15][C:16]([C:19](O)=O)=[N:17][CH:18]=1.C(=O)([O-])[O-].[Na+].[Na+]>O>[CH2:12]([C:13]1[CH:14]=[CH:15][C:16]([C:19]2[NH:7][C:2]3[CH:3]=[CH:4][CH:5]=[CH:6][C:1]=3[N:8]=2)=[N:17][CH:18]=1)[CH2:11][CH2:10][CH3:9]

Participants

5

Reactant 3

HCID 3442Fusaric AcidHCID 7243O-PhenylenediamineHCID 10340Sodium Carbonate

Product 1

HCID 20375060HCID 20375060, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

0.6 g. of o-phenylenediamine, 1 g. of fusaric acid and 10 g. of polyphosphoric acid were heated at 200°-250° C. under a nitrogen gas current with stirring for 1.5 hours. The reaction mixture was diluted with 200 ml. of water and then neutralized with sodium carbonate. The resulting crystals were filtered off, dried and recrystallized from ethyl acetate. 1.2 g. of colorless needles of the product(86% of theory) was obtained. M.P. 138.0°-139.0° C.

Workup

  1. additionThe reaction mixture was diluted with 200 ml
  2. filtrationThe resulting crystals were filtered off
  3. customdried
  4. customrecrystallized from ethyl acetate
  5. customof colorless needles of the product(86% of theory) was obtained

Sources & evidence

ORD record
ord-9b5a8ef942af4aeea556e55d66f3eaaf
Source dataset
uspto-grants-1980_02
Patent number
US04188486

Reaction notes

Loading…