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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 144911Generated: October 26, 2026

1,2-Dimethoxyethane → Methyl 2'-fluoro-5'-(methyloxy)-2-(tetrahydro-2H-pyran-2-yloxy)-1,1'-biphenyl-4-carboxylate

https://huagongshe.com/reaction/144911

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantFluoride IonHCID 28179—
ReactantCesium cationHCID 104967—
Reactant2-Fluoro-5-methoxyphenylboronic acidHCID 4157211—
ReactantMethyl 4-bromo-3-(tetrahydropyran-2-yloxy)benzoateHCID 16747841—
ReactantHCID 178420554HCID 178420554—
ProductMethyl 2'-fluoro-5'-(methyloxy)-2-(tetrahydro-2H-pyran-2-yloxy)-1,1'-biphenyl-4-carboxylateHCID 57707262—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (9/10)
ORD IDord-ab350097916e461b99204359152d4654
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (9/10)