Dimethylamine → HCID 14417382, compound

HRID 1449141Notes

Reaction equation

HRID 1449141 reaction equation
Cl[C:2]1[N:10]=[CH:9][N:8]=[C:7]2[C:3]=1[N:4]=[CH:5][N:6]2[CH2:11][C:12]1[C:17]([Cl:18])=[CH:16][CH:15]=[CH:14][C:13]=1[Cl:19].[CH3:20][NH:21][CH3:22]>CO>[Cl:19][C:13]1[CH:14]=[CH:15][CH:16]=[C:17]([Cl:18])[C:12]=1[CH2:11][N:6]1[CH:5]=[N:4][C:3]2[C:7]1=[N:8][CH:9]=[N:10][C:2]=2[N:21]([CH3:22])[CH3:20]

Participants

4

Reactant 2

HCID 674DimethylamineHCID 14416083HCID 14416083, compound

Product 1

HCID 14417382HCID 14417382, compoundYield 79%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

6-Chloro-9-(2,6-dichlorobenzyl)purine 627 mg, 2.2 g of 20% methanolic dimethylamine and 50 ml of methanol were treated in the same manner as Example 2. By the above procedure there was obtained 504 mg (yield 79%) of 9-(2,6-dichlorobenzyl)-6-dimethylaminopurine as colorless needles, m.p. 174°-175° C.

Sources & evidence

ORD record
ord-b56b0badb1914bd680c1fee25c9f5446
Source dataset
uspto-grants-1980_02
Patent number
US04189485

Reaction notes

Loading…