L-Lysine → Carbon Dioxide

HRID 1449153Notes

Reaction equation

HRID 1449153 reaction equation
C([O:4]C1C=CC(C[C:12]([OH:14])=[O:13])=CC=1Cl)C=C.[NH2:16][C@H:17]([C:23]([OH:25])=[O:24])[CH2:18][CH2:19][CH2:20][CH2:21][NH2:22]>C(O)C.O>[C:12](=[O:14])=[O:13].[C:23](=[O:24])([OH:4])[OH:25].[NH2:16][C@H:17]([C:23]([OH:25])=[O:24])[CH2:18][CH2:19][CH2:20][CH2:21][NH2:22]

Participants

6

Reactant 2

HCID 5962L-LysineHCID 30951Alclofenac

Product 2

HCID 280Carbon DioxideHCID 75124169L-lysine carbonate

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

226.6 g of 4-allyloxy-3-chlorophenylacetic acid are dissolved in 1200 ml of 25% ethyl alcohol. Separately 146 g of lysine are dissolved in water which is then, saturated with CO2, so as to obtain a 30% solution of lysine carbonate.

Sources & evidence

ORD record
ord-803897716b8c4b56815d0b94ad2267db
Source dataset
uspto-grants-1980_02
Patent number
US04189499

Reaction notes

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