huagongshe.com
HRID1449167

反应详情

EQUATION

反应方程式

HRID 1449167 的结构方程式

REACTANTS

反应物

3
结构：OCCCCCCO
HCID12374

1,6-Hexanediol

C6H14O2

结构：C1COCCO1
HCID31275

1,4-Dioxane

C4H8O2

结构：Cc1ccc(S(=O)(=O)O[C@H]2CC[C@@]3(C)C(=CC[C@H]4[C@@H]5CC[C@H]([C@H](C)CCCC(C)C)[C@@]5(C)CC[C@@H]43)C2)cc1
HCID10907651

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@H](OCCCCCCO)CC[C@]4(C)[C@H]3CC[C@]12C
HCID131711720

未命名化合物

收率 52%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCCCCC
溶剂HCID8058

n-Hexane

C6H14

PROCEDURE

实验过程

Using the procedure of Davis, J. Chem. Soc. 178-181 (1962), cholesterol tosylate and 1,6-hexanediol were condensed in refluxing dioxane to provide 52% yield of the title ether as colorless plates from hexane, m.p. 79.5°-81° C.; [α]D25 -28.1°±0.5° C.; IR 3500-3200 (OH), 1100 and 1080 cm-1 (ether); NMR (CDCL3): δ2.8-3.3 (br, 1H, H-1), 3.3-3.75 (2t,4H), 5.4 m, 1H).

WORKUP

后处理

  1. customcondensed