Palladium → 6-methyl-5-(3-(6-(methylamino)pyrimidin-4-yl)pyridin-2-ylamino)isoquinolin-1(2H)-one
Reaction equation
[CH:29]1([P:30]([CH:31]2[CH2:32][CH2:33][CH2:34][CH2:35][CH2:36]2)[c:37]2[cH:38][cH:39][cH:40][cH:41][c:42]2-[c:43]2[cH:44][cH:45][cH:46][cH:47][c:48]2[N:49]([CH3:50])[CH3:51])[CH2:52][CH2:53][CH2:54][CH2:55][CH2:56]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[cH:9][c:10]([NH:14][CH3:15])[n:11][cH:12][n:13]1.[NH2:16][c:17]1[c:18]2[cH:19][cH:20][nH:21][c:22](=[O:28])[c:23]2[cH:24][cH:25][c:26]1[CH3:27].[O:59]=[C:60]([CH:61]=[CH:62][c:63]1[cH:64][cH:65][cH:66][cH:67][cH:68]1)[CH:69]=[CH:70][c:71]1[cH:72][cH:73][cH:74][cH:75][cH:76]1.[O:77]=[C:78]([CH:79]=[CH:80][c:81]1[cH:82][cH:83][cH:84][cH:85][cH:86]1)[CH:87]=[CH:88][c:89]1[cH:90][cH:91][cH:92][cH:93][cH:94]1.[O:95]=[C:96]([CH:97]=[CH:98][c:99]1[cH:100][cH:101][cH:102][cH:103][cH:104]1)[CH:105]=[CH:106][c:107]1[cH:108][cH:109][cH:110][cH:111][cH:112]1.[Pd:57].[Pd:58]>>[c:2]1([NH:16][c:17]2[c:18]3[cH:19][cH:20][nH:21][c:22](=[O:28])[c:23]3[cH:24][cH:25][c:26]2[CH3:27])[n:3][cH:4][cH:5][cH:6][c:7]1-[c:8]1[cH:9][c:10]([NH:14][CH3:15])[n:11][cH:12][n:13]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-22e0d84d604540f3bc4ca376f6e9bc9b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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