Ethyl chloroformate → HCID 20349074, compound

Participants

Reaction Conditions

Reaction Steps

A solution of N-(m-nitrophenyl) hydroxylamine (19.0 g.) in dioxane (100 ml.), water (25 ml.) and sodium bicarbonate (11.0 g.) was cooled to 5° C. Ethyl chloroformate (13.3 g; 11.8 ml.) was added to the solution and the mixture stirred at 5° C. for about 1/2 hour. The reaction mixture was poured into ice water (300 ml.) and the precipitate therefrom was removed by filtering and was dried by standing. The solid product was recrystallized from benzene-hexane mixture and dried under vacuum to yield ethyl (3-nitrophenyl)-N-hydroxyurethane as yellow crystals melting 103°-105° C.

Provenance & Evidence