HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosgene → pyrrolo[1,2-a]quinoxalin-4(5H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosgene | HCID 6371 | — |
| Reactant | 2-(1H-pyrrol-1-yl)aniline | HCID 80123 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | pyrrolo[1,2-a]quinoxalin-4(5H)-one | HCID 2740936 | — |
Reaction Steps
15 g (0.095 mol) of 2-(1-pyrrolyl)aniline is brought to reflux for 1 h 30 min, in 200 cm3 of toluene, in the presence of 50 cm3 of a 20% solution of phosgene in toluene. After cooling, the precipitate formed is filtered off, washed with ethyl ether, dried and recrystallized from acetonitrile (white powder sublimed at 270° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05599812 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-258dd5dc38914bef95f011ce80bb98eb |
| Source note | uspto-grants-1997_02 |