Methyl 3'-nitro[1,1'-biphenyl]-4-carboxylate → methyl 4-(3-aminophenyl)benzoate

Participants

Reaction Steps

In 100 ml of tetrahydrofuran was dissolved 2.70 g of methyl 3'-nitro-biphenyl-4-carboxylate obtained in Reference Example 8. To the solution was added 1.0 g of 10% palladium-on-carbon and the mixture was subjected to catalytic reduction for 2 hours. After removing the catalyst by filtration, the solvent was removed under reduced pressure to obtain 2.34 g of the titled compound.

Provenance & Evidence