Triethylamine → HCID 57013520, compound

Participants

Reaction Steps

To a solution of 2-Chlorosulfonyl-4,5-dimethoxy-benzoic acid methyl ester (0.100 g, 0.339 mmol) in methylene chloride (5 mL) was added triethylamine (0.28 mL, 2.012 mmol) and methyl glycinate.HCl (0.128 g, 1.02 mmol). The mixture was stirred for 2 hours and then diluted with ethyl acetate (50 mL) and 1N HCl (50 mL). The organic fraction was washed with brine and dried over MgSO4. Crystallization from methylene chloride hexane affords the title compound (0.092 g, 78%);

Provenance & Evidence