2-Chloro-N-(1-hydroxy-2-methylpropan-2-yl)thiazole-5-sulfonamide → 2-[5-(3,4-Dichloro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiazole-5-sulfonic acid (2-hydroxy-1,1-dimethyl-ethyl)-amide
Reaction equation
[Cl:1][c:2]1[cH:3][c:4](-[c:9]2[n:10][c:11]3[n:12]([c:13]([C:15]([F:16])([F:17])[F:18])[cH:14]2)[n:19][cH:20][c:21]3[C:22]#[CH:23])[cH:5][cH:6][c:7]1[Cl:8].[OH:24][CH2:25][C:26]([CH3:27])([CH3:28])[NH:29][S:30](=[O:31])(=[O:32])[c:33]1[cH:34][n:35][c:36]([Cl:38])[s:37]1>>[Cl:1][c:2]1[cH:3][c:4](-[c:9]2[n:10][c:11]3[n:12]([c:13]([C:15]([F:16])([F:17])[F:18])[cH:14]2)[n:19][cH:20][c:21]3[C:22]#[C:23][c:36]2[n:35][cH:34][c:33]([S:30]([NH:29][C:26]([CH2:25][OH:24])([CH3:27])[CH3:28])(=[O:31])=[O:32])[s:37]2)[cH:5][cH:6][c:7]1[Cl:8]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-094ae65c0638446081bc45629b38eb81
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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