HCID 86750274, compound → Methyl 6-[2-(2-methoxyethoxy)ethoxy]-1H-indole-2-carboxylate

HRID 1449738Notes

Reaction equation

HRID 1449738 reaction equation
[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][CH2:7][O:8][C:9]1[CH:22]=[CH:21][C:12]([CH:13]=[C:14]([N:18]=[N+]=[N-])[C:15]([O-:17])=[O:16])=[CH:11][CH:10]=1.O[CH2:24]COCCOCCOC(C1C=CC=CC=1)=C(N=[N+]=[N-])C([O-])=O>>[CH3:1][O:2][CH2:3][CH2:4][O:5][CH2:6][CH2:7][O:8][C:9]1[CH:22]=[C:21]2[C:12]([CH:13]=[C:14]([C:15]([O:17][CH3:24])=[O:16])[NH:18]2)=[CH:11][CH:10]=1

Participants

3

Reactant 2

HCID 86750274HCID 86750274, compoundHCID 131719820HCID 131719820, compound

Product 1

HCID 21477681Methyl 6-[2-(2-methoxyethoxy)ethoxy]-1H-indole-2-carboxylate

Procedure

Following the general procedure of EXAMPLE 3, and making non-critical variations but substituting 4-(2-(2-methoxyethoxy)ethoxy)-α-azidocinnamate (PREPARATION 79) for 4-[(2-(2-hydroxyethoxy)ethoxy)ethoxyl-α-azidocinnamate, the title compound is obtained, NMR (300 MHz, CD3OD) 7.59, 7.20, 7.02, 6.87, 4.25, 4.00, 3.96, 3.80, 3.67 and 3.47.

Sources & evidence

ORD record
ord-537287f0c044459b9fe50884fe93ca42
Source dataset
uspto-grants-1997_02
Patent number
US05599930

Reaction notes

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