HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ibuprofen, (+-)- → IBUPROFEN SODIUM SALT
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ibuprofen, (+-)- | HCID 3672 | — |
| Reactant | 2-Phenylpropionic acid | HCID 10296 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Product | IBUPROFEN SODIUM SALT | HCID 45052535 | — |
Reaction Steps
where the phenylpropionic acid is ibuprofen, contact with an aqueous solution of a sodium containing base to produce an aqueous solution of sodium ibuprofen which is separated from the water-immiscible solvent, the aqueous solution then being diluted with acetone to crystallise further-(S)-enriched-sodium-ibuprofen; or
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05599969 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-f170b1443d5144e78c41f7a447636fad |
| Source note | uspto-grants-1997_02 |