HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 3-(bromophenyl)acetate → Ethyl 4-(3-bromophenyl)butanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 3-(bromophenyl)acetate | HCID 11470552 | — |
| Reactant | Ethyl 4-(4-bromophenyl)butanoate | HCID 12870375 | — |
| Product | Ethyl 4-(3-bromophenyl)butanoate | HCID 11492759 | — |
Reaction Steps
Employing the same general multistep preparation as for ethyl 4-(4-bromophenyl) butanoate (Compound C), 60 g (246 mmol) of ethyl (3-bromophenyl)acetate (Compound B) was converted into the title compound (oil) using 255 ml (255 mmol) of diisobutylaluminum hydride (DIBAL--H, 1M in hexane), 85.8 g (250 mmol) of (carbethoxymethylene) triphenylphosphorane and 1.7 g of 10% Pd/C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05599967 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-2d15514135744a7a8add46dc66b629ce |
| Source note | uspto-grants-1997_02 |