Diphenylpropionic acid → HCID 86750286, compound

HRID 1449817Notes

Reaction equation

HRID 1449817 reaction equation
[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][NH:8][CH2:9][CH:10]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[OH:11].[C:18]1([CH:24]([C:29]2[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=2)[CH2:25][C:26](O)=[O:27])[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.[C:35]([O:38]CC)(=[O:37])C.[CH3:41][OH:42]>>[OH:11][CH:10]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH2:9][NH:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][O:1][C:26](=[O:27])[CH2:25][CH:24]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:29]1[CH:34]=[CH:33][CH:32]=[CH:31][CH:30]=1.[C:35]([O-:38])(=[O:37])[C:41]([O-:1])=[O:42]

Participants

4

Reactant 3

HCID 64798Diphenylpropionic acidHCID 21584119Ethylacetate methanolHCID 54456417HCID 54456417, compound

Product 1

HCID 86750286HCID 86750286, compound

Procedure

According to method II from 2-(6-hydroxy-1-hexylamino)-1-phenylethanol and 3,3-diphenylpropionic acid. Working up by means of chromatography (ethyl acetate/methanol 1:1). Recrystallized as the oxalate from acetone. Melting point: 136°-139° C.

Workup

  1. customRecrystallized as the oxalate from acetone

Sources & evidence

ORD record
ord-f8b731cf915842b0b19435440c8f1383
Source dataset
uspto-grants-1997_02
Patent number
US05599966

Reaction notes

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