Benzenepentanoic acid → HCID 86750288, compound

HRID 1449818Notes

Reaction equation

HRID 1449818 reaction equation
[OH:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][NH:8][CH2:9][CH:10]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[OH:11].[C:18]1([CH2:24][CH2:25][CH2:26][CH2:27][C:28](O)=[O:29])[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.[C:31]([O:34]CC)(=[O:33])C.[CH3:37][OH:38]>>[OH:11][CH:10]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH2:9][NH:8][CH2:7][CH2:6][CH2:5][CH2:4][CH2:3][CH2:2][O:1][C:28](=[O:29])[CH2:27][CH2:26][CH2:25][CH2:24][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1.[C:31]([O-:34])(=[O:33])[C:37]([O-:1])=[O:38]

Participants

4

Reactant 3

HCID 16757Benzenepentanoic acidHCID 21584119Ethylacetate methanolHCID 54456417HCID 54456417, compound

Product 1

HCID 86750288HCID 86750288, compound

Procedure

According to method II from 2-(6-hydroxy-1-hexylamino)-1-phenylethanol and 5-phenylvaleric acid. Working up by means of chromatography (ethyl acetate/methanol 1:1). Recrystallized as the oxalate from acetone. Melting point: 130°-134° C.

Workup

  1. customRecrystallized as the oxalate from acetone

Sources & evidence

ORD record
ord-b7f60b8a45ef47d99b379fc8770a4b6d
Source dataset
uspto-grants-1997_02
Patent number
US05599966

Reaction notes

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