HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 178507833, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Benzenemethanol, 4-amino-alpha-(aminomethyl)-3,5-dichloro- | HCID 217242 | — |
| Reactant | HCID 178520548 | HCID 178520548 | — |
| Solvent | Triethylamine | HCID 8471 | — |
| Product | HCID 178507833 | HCID 178507833 | — |
Reaction Steps
According to method I (dimethylformamide, 2 hours at 90° C.) from 2-amino-1-(4-amino-3,5-dichlorophenyl)ethanol and {4-(bromomethyl)[trans]cyclohexylmethyl}(4-phenyl)butanoate. Working up by means of chromatography (ethyl acetate/petroleum ether 60-80/triethylamine 4:2:1). Recrystallized as the maleate from ethyl acetate. Melting point: 155°-157° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05599966 |
| Source dataset | uspto-grants-1997_02 |
| ORD ID | ord-d69b24b3b76640468ddc5d971c3f437e |
| Source note | uspto-grants-1997_02 |