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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1449825Generated: November 3, 2026

Dimethylformamide → HCID 86750293, compound

https://huagongshe.com/reaction/1449825

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantBenzenemethanol, 4-amino-alpha-(aminomethyl)-3,5-dichloro-HCID 217242—
ReactantHCID 54423614HCID 54423614—
SolventEthyl acetate methanol triethylamineHCID 21980445—
ProductHCID 86750293HCID 86750293—

Reaction Steps

According to method I (dimethylformamide, 2 hours at 90° C.) from 2-amino-1-(4-amino-3,5-dichlorophenyl)ethanol and (3-phenylpropyl)-4-bromobutanoate. Working up by means of chromatography (ethyl acetate/methanol/triethylamine 20:2:1). Recrystallized as the maleate from acetone. Melting point: 70°-71° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05599966
Source datasetuspto-grants-1997_02
ORD IDord-4ca200f9a45945949be329e08eb0b51a
Source noteuspto-grants-1997_02